SCH900776 S-isomer
CAS No. 891494-64-7
SCH900776 S-isomer( MK-8776 S-isomer )
Catalog No. M17644 CAS No. 891494-64-7
SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).
SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
2MG | 58 | In Stock |
|
5MG | 87 | In Stock |
|
10MG | 141 | In Stock |
|
25MG | 250 | In Stock |
|
50MG | 402 | In Stock |
|
100MG | 593 | In Stock |
|
200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameSCH900776 S-isomer
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NoteResearch use only, not for human use.
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Brief DescriptionSCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).
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DescriptionSCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM).
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In Vitro——
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In Vivo——
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SynonymsMK-8776 S-isomer
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PathwayOthers
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TargetOther Targets
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RecptorCDK2| Chk1| Chk2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number891494-64-7
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Formula Weight376.25
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Molecular FormulaC15H18BrN7
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 100 mg/mL; 265.78 mM
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SMILESCn1cc(cn1)c1c2nc(c(c(n2nc1)N)Br)[C@H]1CCCNC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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H-Abu-OH
L-alpha-Aminobutyric acid also known as (S)-2-aminobutanoic acid homoalanine 2-AABA ethylglycine or L-butyrine is a member of the class of compounds known as L-alpha-amino acids. L-alpha-Aminobutyric acid is a non-proteogenic amino acid that can be found in the human kidney in liver tissues and in most biofluids or excreta (e.g. feces breast milk urine and blood).
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Euchrestaflavanone B
Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. Euchrestaflavanone B may function by inhibiting oncogenic disease, at least in part, through the inhibition of protein kinase CKII activity.
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Bidenoside C
Bidenoside C is a flavonoid found in brazilian propolis, the first of its kind to be isolated from a herb of the genus Leech, and has anti-proliferative activity against cancer cells.