SCH900776 S-isomer

CAS No. 891494-64-7

SCH900776 S-isomer( MK-8776 S-isomer )

Catalog No. M17644 CAS No. 891494-64-7

SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).

SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 58 In Stock
5MG 87 In Stock
10MG 141 In Stock
25MG 250 In Stock
50MG 402 In Stock
100MG 593 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    SCH900776 S-isomer
  • Note
    Research use only, not for human use.
  • Brief Description
    SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).
  • Description
    SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MK-8776 S-isomer
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CDK2| Chk1| Chk2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    891494-64-7
  • Formula Weight
    376.25
  • Molecular Formula
    C15H18BrN7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 100 mg/mL; 265.78 mM
  • SMILES
    Cn1cc(cn1)c1c2nc(c(c(n2nc1)N)Br)[C@H]1CCCNC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Guzi TJ, et al. Mol Y Ther, 2011, 10(4), 591-602.
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